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The study demonstrated that Semax significantly increased 5-HIAA in the striatum — raising tissue content by roughly 25% and extracellular levels up to 180% over 1-4 hours — indicating a positive modulatory effect on the striatal serotonergic system

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4.4 Ferroptosis in osteosarcoma Osteosarcoma is a cancerous tumor of the bone characterized by high mortality rates, significant disability, and frequent metastasis and recurrence, primarily affecting the bones and lungs (184)